*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : BV7985000
CHEMICAL NAME           : Androsta-1,4-diene-2-carboxaldehyde,
                          11-alpha,17-beta-dihydroxy-17-methyl-3-oxo-
CAS REGISTRY NUMBER     : 2454-11-7
LAST UPDATED            : 199512
DATA ITEMS CITED        : 5
MOLECULAR FORMULA       : C21-H28-O4
MOLECULAR WEIGHT        : 344.49
WISWESSER LINE NOTATION : L E5 B666 OV AHTTT&J A1 CQ E1 FQ F1 PVH
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   *   11-alpha,17-beta-Dihydroxy-17-methyl-3-oxoandrosta-1,4-diene-2-carboxald
     ehyde
   * Esiclene
   * Formebolone
   * Formyldienolone
   * 2-Formyl-11-alpha-hydroxy-delta(sup 1)-methyltestosterone
   * 2-Formyl-17-alpha-methylandrosta-1,4-diene-11-alpha,17-beta-diol-3-one
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD - Lethal dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : >1 gm/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   GIMCAK Gazzetta Internazionale di Medicina e Chirurgia. (Rome)  V.28-77,
   1920-1972.  Discontinued  Volume(issue)/page/year: 76,400,1971
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 104 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   GIMCAK Gazzetta Internazionale di Medicina e Chirurgia. (Rome)  V.28-77,
   1920-1972.  Discontinued  Volume(issue)/page/year: 76,400,1971
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 270 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   GIMCAK Gazzetta Internazionale di Medicina e Chirurgia. (Rome)  V.28-77,
   1920-1972.  Discontinued  Volume(issue)/page/year: 76,400,1971
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 187 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   GIMCAK Gazzetta Internazionale di Medicina e Chirurgia. (Rome)  V.28-77,
   1920-1972.  Discontinued  Volume(issue)/page/year: 76,400,1971
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 293 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   GIMCAK Gazzetta Internazionale di Medicina e Chirurgia. (Rome)  V.28-77,
   1920-1972.  Discontinued  Volume(issue)/page/year: 76,400,1971
 
                            *** END OF RECORD ***