*** CHEMICAL IDENTIFICATION *** RTECS NUMBER : BX7175000 CHEMICAL NAME : Aniline, N,N-dimethyl-p-nitroso- CAS REGISTRY NUMBER : 138-89-6 BEILSTEIN REFERENCE NO. : 0607293 REFERENCE : 4-12-00-01558 (Beilstein Handbook Reference) LAST UPDATED : 199701 DATA ITEMS CITED : 4 MOLECULAR FORMULA : C8-H10-N2-O MOLECULAR WEIGHT : 150.20 WISWESSER LINE NOTATION : ONR DN1&1 COMPOUND DESCRIPTOR : Tumorigen Mutagen SYNONYMS/TRADE NAMES : * Accelerine * Benzenamine, N,N-dimethyl-4-nitroso- * p-(Dimethylamino)nitrosobenzene * 4-(Dimethylamino)nitrosobenzene * N,N-Dimethyl-p-nitrosoaniline * N,N-Dimethyl-4-nitrosobenzenamine * Dimethyl(p-nitrosophenyl)amine * NCI-C01821 * NDMA * p-Nitroso-N,N-dimethylaniline * 4-Nitrosodimethylaniline * Paranitrosodimethylanilide * Ultra Brilliant Blue P *** HEALTH HAZARD DATA *** ** ACUTE TOXICITY DATA ** TYPE OF TEST : LDLo - Lowest published lethal dose ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Mammal - species unspecified DOSE/DURATION : 650 mg/kg TOXIC EFFECTS : Behavioral - somnolence (general depressed activity) Behavioral - convulsions or effect on seizure threshold Kidney, Ureter, Bladder - hematuria REFERENCE : JIDHAN Journal of Industrial Hygiene. (Cambridge, MA) V.1-17, 1919-35. For publisher information, see AEHLAU. Volume(issue)/page/year: 13,87,1931 ** TUMORIGENIC DATA ** TYPE OF TEST : TDLo - Lowest published toxic dose ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - rat DOSE/DURATION : 7300 mg/kg/1Y-C TOXIC EFFECTS : Tumorigenic - equivocal tumorigenic agent by RTECS criteria Gastrointestinal - tumors Blood - lymphoma, including Hodgkin's disease REFERENCE : PUOMA5 Proceedings of the University of Otago Medical School. (Otago Medical School Research Soc., Box 913, Dunedin, New Zealand) V.1- 1922- Volume(issue)/page/year: 46,68,1968 ** MUTATION DATA ** TYPE OF TEST : Mutation in microorganisms TEST SYSTEM : Bacteria - Salmonella typhimurium DOSE/DURATION : 10 ug/plate REFERENCE : ENMUDM Environmental Mutagenesis. (New York, NY) V.1-9, 1979-87. For publisher information, see EMMUEG. Volume(issue)/page/year: 8(Suppl 7),1,1986 *** STATUS IN U.S. *** EPA TSCA Section 8(b) CHEMICAL INVENTORY *** END OF RECORD ***