*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : BX9540000
CHEMICAL NAME           : Aniline, 2,2'-dithiobis-
CAS REGISTRY NUMBER     : 1141-88-4
BEILSTEIN REFERENCE NO. : 0914032
REFERENCE               : 4-13-00-00920 (Beilstein Handbook Reference)
LAST UPDATED            : 199703
DATA ITEMS CITED        : 5
MOLECULAR FORMULA       : C12-H12-N2-S2
MOLECULAR WEIGHT        : 248.38
WISWESSER LINE NOTATION : ZR BSSR BZ
COMPOUND DESCRIPTOR     : Primary Irritant
SYNONYMS/TRADE NAMES :
   * Aniline, 2,2'-dithiodi-
   * Benzenamine, 2,2'-dithiobis-
   * Bis(2-aminophenyl)disulfide
   * Disulfide, bis(o-aminophenyl)-
   * o,o'-Diamino diphenyl disulfide
   * 2,2'-Diaminodiphenyl disulfide
   * Disulfide, 1,1'-bis(2-aminophenyl)
   * o,o-Dithio-bis-aniline
   * 2,2'-Dithiobis(aniline)
   * 2,2'-Dithiodianiline
   * Intramine
   * USAF AB-315
 
                       *** HEALTH HAZARD DATA ***
 
                      ** SKIN/EYE IRRITATION DATA **
 
TYPE OF TEST            : Standard Draize test
ROUTE OF EXPOSURE       : Administration into the eye
SPECIES OBSERVED        : Rodent - rabbit
DOSE/DURATION           : 50 ug/24H
REACTION SEVERITY       : Severe
REFERENCE :
   85JCAE "Prehled Prumyslove Toxikologie; Organicke Latky," Marhold, J.,
   Prague, Czechoslovakia, Avicenum, 1986  Volume(issue)/page/year: -,1005,1986
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 50 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   NTIS** National Technical Information Service.  (Springfield, VA 22161)
   Formerly U.S. Clearinghouse for Scientific & Technical Information.
   Volume(issue)/page/year: AD277-689
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 178 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   CSLNX* U.S. Army Armament Research & Development Command, Chemical Systems
   Laboratory, NIOSH Exchange Chemicals.  (Aberdeen Proving Ground, MD 21010)
   Volume(issue)/page/year: NX#00263
 
                 ** OTHER MULTIPLE DOSE TOXICITY DATA **
 
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 434 mg/kg/7D-I
TOXIC EFFECTS :
   Endocrine - changes in spleen weight
   Blood - pigmented or nucleated red blood cells
   Nutritional and Gross Metabolic - changes in iron
REFERENCE :
   JJATDK JAT, Journal of Applied Toxicology.  (John Wiley & Sons Ltd., Baffins
   Lane, Chichester, W. Sussex PO19 1UD, UK)  V.1-    1981-
   Volume(issue)/page/year: 5,414,1985

                          *** STATUS IN U.S. ***
 
   EPA TSCA Section 8(b) CHEMICAL INVENTORY

 
                            *** END OF RECORD ***