*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : BZ4385000
CHEMICAL NAME           : o-Anisic acid
CAS REGISTRY NUMBER     : 579-75-9
BEILSTEIN REFERENCE NO. : 0509929
REFERENCE               : 4-10-00-00130 (Beilstein Handbook Reference)
LAST UPDATED            : 199701
DATA ITEMS CITED        : 5
MOLECULAR FORMULA       : C8-H8-O3
MOLECULAR WEIGHT        : 152.16
WISWESSER LINE NOTATION : QVR BO1
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * 2-Anisic acid
   * Benzoic acid, 2-methoxy-
   * Kyselina 2-methoxybenzoova
   * o-Methoxybenzoic acid
   * 2-Methoxybenzoic acid
   * O-Methylsalicylic acid
   * Salicylic acid methyl ether
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 3 gm/kg
TOXIC EFFECTS :
   Behavioral - excitement
   Behavioral - muscle contraction or spasticity
REFERENCE :
   BSRSA6 Bulletin de la Societe Royale des Sciences de Liege.  (Societe Royale
   des Sciences de Liege, Universite de Liege, 15, Ave des Tilleuls, B-4000
   Liege, Belgium)  V.1-    1932-  Volume(issue)/page/year: 47,202,1978
 
TYPE OF TEST            : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 2750 mg/kg
TOXIC EFFECTS :
   Behavioral - excitement
   Behavioral - muscle contraction or spasticity
REFERENCE :
   BSRSA6 Bulletin de la Societe Royale des Sciences de Liege.  (Societe Royale
   des Sciences de Liege, Universite de Liege, 15, Ave des Tilleuls, B-4000
   Liege, Belgium)  V.1-    1932-  Volume(issue)/page/year: 47,202,1978
 
TYPE OF TEST            : LD - Lethal dose
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : >500 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   CBCCT* "Summary Tables of Biological Tests," National Research Council
   Chemical-Biological Coordination Center.  (National Academy of Science
   Library, 2101 Constitution Ave., NW, Washington, DC 20418)
   Volume(issue)/page/year: 6,52,1954
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 300 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   CKFRAY Ceskoslovenska Farmacie.  (PNS-Ustredni Expedice a Dovoz Tisku,
   Kafkova 19, 160 00 Prague 6, Czechoslovakia)  V.1-    1952-
   Volume(issue)/page/year: 31,236,1982

                          *** STATUS IN U.S. ***
 
   EPA TSCA Section 8(b) CHEMICAL INVENTORY

 
                            *** END OF RECORD ***