*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : BZ9625000
CHEMICAL NAME           : Anisole, 2,3,5,6-tetrachloro-4-nitro-
CAS REGISTRY NUMBER     : 2438-88-2
BEILSTEIN REFERENCE NO. : 2382408
REFERENCE               : 3-06-00-00842 (Beilstein Handbook Reference)
LAST UPDATED            : 199612
DATA ITEMS CITED        : 4
MOLECULAR FORMULA       : C7-H3-Cl4-N-O3
MOLECULAR WEIGHT        : 290.91
WISWESSER LINE NOTATION : WNR BG CG EG FG DO1
COMPOUND DESCRIPTOR     : Tumorigen
                          Mutagen
SYNONYMS/TRADE NAMES :
   * Benzene, 1,2,4,5-tetrachloro-3-methoxy-6-nitro-
   * ENT 22,335
   * NCI-C03032
   * 4-Nitro-2,3,5,6-tetrachloranisole
   * TCNA
   * 1,2,4,5-Tetrachloro-3-methoxy-6-nitrobenzene
   * Tetrachloronitroanisole
   * 2,3,5,6-Tetrachloro-4-nitroanisole
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 260 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   IHFCAY Industrial Hygiene Foundation of America, Chemical and Toxicological
   Series, Bulletin. (Pittsburgh, PA)  1947-69.  Volume(issue)/page/year:
   6,1,1967
 
                            ** MUTATION DATA **
 
TYPE OF TEST            : Mutation in mammalian somatic cells
TEST SYSTEM             : Rodent - mouse Lymphocyte
DOSE/DURATION           : 5 mg/L
REFERENCE :
   EMMUEG Environmental and Molecular Mutagenesis.  (Alan R. Liss, Inc., 41 E.
   11th St., New York, NY 10003)  V.10-    1987-  Volume(issue)/page/year:
   12,85,1988

                          *** STATUS IN U.S. ***
 
   EPA GENETOX PROGRAM 1988, Negative: Carcinogenicity-mouse/rat
   
   NCI Carcinogenesis Bioassay (feed);no evidence:mouse,rat
   NCITR* National Cancer Institute Carcinogenesis Technical Report Series.
   (Bethesda, MD)  No.0-205. For publisher information, see NTPTR*.
   Volume(issue)/page/year: NCI-TR-114,78

 
                            *** END OF RECORD ***