*** CHEMICAL IDENTIFICATION *** RTECS NUMBER : UO8440545 CHEMICAL NAME : 1H-Purine-2,6-dione, 7-((4-(dimethylamino)phenyl)methyl)-3,7-dihydro-1,3-d imethyl-, monohydrochloride CAS REGISTRY NUMBER : 1703-49-7 LAST UPDATED : 199704 DATA ITEMS CITED : 3 MOLECULAR FORMULA : C16-H19-N5-O2.Cl-H MOLECULAR WEIGHT : 349.86 COMPOUND DESCRIPTOR : Drug SYNONYMS/TRADE NAMES : * (p-Dimethylamino benzyl)-7 dimethyl-1,3 xanthine chlorhydrate * p-Dimethylamino-benzyl theophylline chlorhydrate * LJ 278 * Theophylline, 7-(p-(dimethylamino)benzyl)-, hydrochloride *** HEALTH HAZARD DATA *** ** ACUTE TOXICITY DATA ** TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 660 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : FMXXAJ French Medicament Patent Document. (U.S. Patent and Trademark Office, Foreign Patents, Washington, DC 20231) Discontinued. Volume(issue)/page/year: #3586M TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Subcutaneous SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 630 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : FMXXAJ French Medicament Patent Document. (U.S. Patent and Trademark Office, Foreign Patents, Washington, DC 20231) Discontinued. Volume(issue)/page/year: #3586M TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intravenous SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 82500 ug/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : FMXXAJ French Medicament Patent Document. (U.S. Patent and Trademark Office, Foreign Patents, Washington, DC 20231) Discontinued. Volume(issue)/page/year: #3586M *** END OF RECORD ***