*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : UO8976000
CHEMICAL NAME           : Purine, 6-(methylthio)-
CAS REGISTRY NUMBER     : 50-66-8
LAST UPDATED            : 199709
DATA ITEMS CITED        : 2
MOLECULAR FORMULA       : C6-H6-N4-S
MOLECULAR WEIGHT        : 166.22
WISWESSER LINE NOTATION : T56 BM DN FN HNJ IS1
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * 6-Methylmercaptopurine
   * 6-(Methylthio)purine
   * 1H-Purine, 6-(methylthio)-
   * SQ 8343
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Parenteral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 115 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   JPMSAE Journal of Pharmaceutical Sciences.  (American Pharmaceutical Assoc.,
   2215 Constitution Ave., NW, Washington, DC 20037)  V.50-    1961-
   Volume(issue)/page/year: 71,618,1982
 
TYPE OF TEST            : LD10 - Lethal Dose
ROUTE OF EXPOSURE       : Unreported
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 94 mg/kg
TOXIC EFFECTS :
   Gastrointestinal - other changes
REFERENCE :
   PMDCAY Progress in Medical Chemistry.  (Elsevier Science Pub. Co., Inc., 52
   Vanderbilt Ave., New York, NY 10017)  V.1-    1961- Volume(issue)/page/year:
   7,69,1970
 
                            *** END OF RECORD ***