*** CHEMICAL IDENTIFICATION ***
RTECS NUMBER : UP0270000
CHEMICAL NAME : 9H-Purine-6-thiol, 9-ethyl-
CAS REGISTRY NUMBER : 5427-20-3
OTHER CAS REGISTRY NOS. : 17416-85-2
BEILSTEIN REFERENCE NO. : 0162062
REFERENCE : 5-26-13-00225 (Beilstein Handbook Reference)
LAST UPDATED : 199612
DATA ITEMS CITED : 3
MOLECULAR FORMULA : C7-H8-N4-S
MOLECULAR WEIGHT : 180.25
WISWESSER LINE NOTATION : T56 BN DN FN HNJ D2 ISH
COMPOUND DESCRIPTOR : Drug
SYNONYMS/TRADE NAMES :
* 9-Ethyl-1,9-dihydro-6H-purine-6-thione
* 9-Ethyl-6-mercaptopurine
* 9-Ethyl-6-MP
* NSC 14575
* 9H-Purine-6(1H)-thione, 9-ethyl-
* 6H-Purine-6-thione, 9-ethyl-1,9-dihydro-
*** HEALTH HAZARD DATA ***
** ACUTE TOXICITY DATA **
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Intraperitoneal
SPECIES OBSERVED : Rodent - rat
DOSE/DURATION : 400 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
ADTEAS Advances in Teratology. (New York, NY) V.1-5, 1966-72.
Discontinued. Volume(issue)/page/year: 3,181,1968
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Intraperitoneal
SPECIES OBSERVED : Rodent - mouse
DOSE/DURATION : 289 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
NCISP* National Cancer Institute Screening Program Data Summary,
Developmental Therapeutics Program. (Bethesda, MD 20205)
Volume(issue)/page/year: JAN1986
TYPE OF TEST : LD10 - Lethal Dose
ROUTE OF EXPOSURE : Unreported
SPECIES OBSERVED : Rodent - mouse
DOSE/DURATION : 52 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
PMDCAY Progress in Medical Chemistry. (Elsevier Science Pub. Co., Inc., 52
Vanderbilt Ave., New York, NY 10017) V.1- 1961- Volume(issue)/page/year:
7,69,1970
*** END OF RECORD ***