*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : UP0530000
CHEMICAL NAME           : Purine-6-thiol, 3-oxide, monohydrate
LAST UPDATED            : 198910
DATA ITEMS CITED        : 1
MOLECULAR FORMULA       : C5-H4-N4-O-S.H2-O
MOLECULAR WEIGHT        : 186.21
WISWESSER LINE NOTATION : T56 BM DN FN HNJ FO ISH &QH
COMPOUND DESCRIPTOR     : Tumorigen
SYNONYMS/TRADE NAMES :
   * 6-Mercaptopurine 3-N-oxide monohydrate
   * 3-N-Oxide purin-6-thiol monohydrate
 
                       *** HEALTH HAZARD DATA ***
 
                          ** TUMORIGENIC DATA **
 
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 6500 mg/kg/26W-I
TOXIC EFFECTS :
   Tumorigenic - neoplastic by RTECS criteria
   Tumorigenic - tumors at site of application
REFERENCE :
   CNREA8 Cancer Research. (Public Ledger Building, Suit 816, 6th & Chestnut
   Sts., Philadelphia, PA 19106)  V.1-    1941-  Volume(issue)/page/year:
   27,925,1967
 
                            *** END OF RECORD ***