*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : UP6130000
CHEMICAL NAME           : 2H-Pyran-2-acetic acid,
                          tetrahydro-alpha,5-dimethyl-6-(2,4,6,12-tetrahydroxy-
                          1,3,5,11,13,15- hexamethyl-9,13-octadecadienyl)-
CAS REGISTRY NUMBER     : 91920-88-6
BEILSTEIN REFERENCE NO. : 5663898
LAST UPDATED            : 199612
DATA ITEMS CITED        : 2
MOLECULAR FORMULA       : C33-H60-O7
MOLECULAR WEIGHT        : 568.93
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * Griseochelin
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 1 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   JANTAJ Journal of Antibiotics.  (Japan Antibiotics Research Assoc., 2-20-8
   Kamiosaki, Shinagawa-ku, Tokyo, 141, Japan)  V.2-5, 1948-52;  V.21- 1968-
   Volume(issue)/page/year: 37,836,1984
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 500 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   JANTAJ Journal of Antibiotics.  (Japan Antibiotics Research Assoc., 2-20-8
   Kamiosaki, Shinagawa-ku, Tokyo, 141, Japan)  V.2-5, 1948-52;  V.21- 1968-
   Volume(issue)/page/year: 37,836,1984
 
                            *** END OF RECORD ***