*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : UQ0350000
CHEMICAL NAME           : 6aH(S)-pyrano(2",3":5',4')furo(2',3':5,6)azuleno(2,3-
                          c)pyridine-5,13-dione, 8,9,10,10a-
                          tetrahydro-3,8-dimethyl-1-propyl-9,10,10a,11-tetrahyd
                          roxy- (8R,9R,10S,10aR)-
CAS REGISTRY NUMBER     : 65445-21-8
BEILSTEIN REFERENCE NO. : 1095666
LAST UPDATED            : 199612
DATA ITEMS CITED        : 2
MOLECULAR FORMULA       : C23-H23-N-O8
MOLECULAR WEIGHT        : 441.47
WISWESSER LINE NOTATION : T F6 D5 B756 CV EO GO PV SNTT&&&J H1 IQ JQ R3 T1
SYNONYMS/TRADE NAMES :
   * Pigment A
   * Ro 21-1660/002
   * Rubrolone
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : >4 gm/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   JANTAJ Journal of Antibiotics.  (Japan Antibiotics Research Assoc., 2-20-8
   Kamiosaki, Shinagawa-ku, Tokyo, 141, Japan)  V.2-5, 1948-52;  V.21- 1968-
   Volume(issue)/page/year: 31,1218,1978
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 930 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   JANTAJ Journal of Antibiotics.  (Japan Antibiotics Research Assoc., 2-20-8
   Kamiosaki, Shinagawa-ku, Tokyo, 141, Japan)  V.2-5, 1948-52;  V.21- 1968-
   Volume(issue)/page/year: 31,1218,1978
 
                            *** END OF RECORD ***