*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : UQ0517000
CHEMICAL NAME           : 2H-Pyran-2-one,
                          5,6-dihydro-4-methoxy-6-(3,4-(methylenedioxy)styryl)-
                          , (R)-
CAS REGISTRY NUMBER     : 495-85-2
BEILSTEIN REFERENCE NO. : 0091701
REFERENCE               : 5-19-10-00456 (Beilstein Handbook Reference)
LAST UPDATED            : 199612
DATA ITEMS CITED        : 2
MOLECULAR FORMULA       : C15-H14-O5
MOLECULAR WEIGHT        : 274.29
WISWESSER LINE NOTATION : T56 BO DO CHJ G1U1- FT6OV CUTJ DO1
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   *   (R-(E))-6-(2-(1,3-Benzodioxol-5-yl)ethenyl)-5,6-dihydro-4-methoxy-2H-pyr
     an-2-one
   * (R)-5,6-Dihydro-4-methoxy-6-(3,4-(methylenedioxy)styryl)-2H-pyran-2-one
   * 5-Hydroxy-3-methoxy-7-(3,4-(methylenedioxy)phenyl)-2,6-heptadienoic acid  
   gamma-lactone
   * Kavahin
   * Kavatin
   *   4-Methoxy-6-(beta-(3',4'-methylenedioxyphenyl)vinyl)-5,6-dihydro-alpha-p
     yrone
   * Methysticin
   * (+)-Methysticin
   * 2H-Pyran-2-one,  
   6-(2-(1,3-benzodioxol-5-yl)ethenyl)-5,6-dihydro-4-methoxy-, (R-(E))-
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 530 mg/kg
TOXIC EFFECTS :
   Behavioral - anticonvulsant
REFERENCE :
   AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans
   Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium)  V.4-   
   1898-  Volume(issue)/page/year: 177,261,1969
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 49 mg/kg
TOXIC EFFECTS :
   Behavioral - anticonvulsant
REFERENCE :
   AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans
   Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium)  V.4-   
   1898-  Volume(issue)/page/year: 177,261,1969
 
                            *** END OF RECORD ***