*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : UQ4552000
CHEMICAL NAME           : Pyrazino(1',2':1,6)pyrido(3,4-b)indole,
                          1,2,3,4,6,7,12,12a-octahydro-2-(3,3-diphenyl-2-
                          propenyl)-
CAS REGISTRY NUMBER     : 77294-03-2
BEILSTEIN REFERENCE NO. : 4582368
LAST UPDATED            : 199612
DATA ITEMS CITED        : 1
MOLECULAR FORMULA       : C29-H29-N3
MOLECULAR WEIGHT        : 419.61
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   *   1,2,3,4,6,7,12,12a-Octahydro-2-(3,3-diphenyl-2-propenyl)pyrazino(1',2':1
     ,6)pyrido(3,4-b)indole
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 800 mg/kg
TOXIC EFFECTS :
   Behavioral - somnolence (general depressed activity)
   Kidney, Ureter, Bladder - urine volume increased
   Biochemical - Metabolism (Intermediary) - effect on inflammation or
   mediation of inflammation
REFERENCE :
   IJSBDB Indian Journal of Chemistry, Section B: Organic Chemistry, Including
   Medicinal Chemistry. (Publications & Information Directorate, Council of
   Scientific and Industrial Research (CSIR), Hillside Rd., New Delhi 110 012,
   India)  V.14B-    1976-  Volume(issue)/page/year: 19,882,1980
 
                            *** END OF RECORD ***