*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : UQ4728000
CHEMICAL NAME           : 6H-Pyrazino(1,2-c)pyrimidin-6-one,
                          octahydro-7-ethyl-2-methyl-
CAS REGISTRY NUMBER     : 25143-13-9
LAST UPDATED            : 198608
DATA ITEMS CITED        : 2
MOLECULAR FORMULA       : C10-H19-N3-O
MOLECULAR WEIGHT        : 197.32
WISWESSER LINE NOTATION : T66 ANVN HNTJ C2 H1
COMPOUND DESCRIPTOR     : Drug
                          Mutagen
SYNONYMS/TRADE NAMES :
   * Centperazine
   * 7-Ethyl-2-methyloctahydro-6H-pyrazino(1,2-c)pyrimidin-6-one
   * 3-Ethyl-8-methyl-1,3,8-triazabicyclo(4.4.0)decan-2-one
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 300 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   JPPMAB Journal of Pharmacy and Pharmacology.  (Pharmaceutical Soc. of Great
   Britain, 1 Lambeth High St., London SEI 7JN, UK)  V.1-    1949-
   Volume(issue)/page/year: 22,306,1970
 
                            ** MUTATION DATA **
 
TYPE OF TEST            : Mutation test systems - not otherwise specified
TEST SYSTEM             : Non-mammalian species
DOSE/DURATION           : 10 mmol/L
REFERENCE :
   CUSCAM Current Science.  (Current Science Assoc., Sadashivanagar P.O.,
   Bangalore 560 080, India) V.1-    1932-  Volume(issue)/page/year:
   52,303,1983
 
                            *** END OF RECORD ***