*** CHEMICAL IDENTIFICATION *** RTECS NUMBER : UQ4730325 CHEMICAL NAME : 2H,10H-Pyrazino(1,2-alpha)pyrrolo(2,1-c)(1,4)benzodia zepine, 1,3,4,14b-tetrahydro-2-methyl-, (Z)-2-butenedioate (1:1) CAS REGISTRY NUMBER : 71576-41-5 LAST UPDATED : 199512 DATA ITEMS CITED : 3 MOLECULAR FORMULA : C16-H19-N3.C4-H4-O4 MOLECULAR WEIGHT : 369.46 SYNONYMS/TRADE NAMES : * Aptazapine maleate * CGS 7525A *** HEALTH HAZARD DATA *** ** OTHER MULTIPLE DOSE TOXICITY DATA ** TYPE OF TEST : TDLo - Lowest published toxic dose ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - rat DOSE/DURATION : 43680 mg/kg/2Y-I TOXIC EFFECTS : Cardiac - other changes Endocrine - other changes Kidney, Ureter, Bladder - other changes REFERENCE : TOXID9 Toxicologist. (Soc. of Toxicology, Inc., 475 Wolf Ledge Parkway, Akron, OH 44311) V.1- 1981- Volume(issue)/page/year: 6,46,1986 TYPE OF TEST : TDLo - Lowest published toxic dose ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 32760 mg/kg/78W-I TOXIC EFFECTS : Cardiac - other changes Liver - other changes Kidney, Ureter, Bladder - other changes REFERENCE : TOXID9 Toxicologist. (Soc. of Toxicology, Inc., 475 Wolf Ledge Parkway, Akron, OH 44311) V.1- 1981- Volume(issue)/page/year: 6,46,1986 TYPE OF TEST : TDLo - Lowest published toxic dose ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Mammal - dog DOSE/DURATION : 1092 mg/kg/52W-I TOXIC EFFECTS : Brain and Coverings - other degenerative changes Liver - other changes Kidney, Ureter, Bladder - other changes REFERENCE : TOXID9 Toxicologist. (Soc. of Toxicology, Inc., 475 Wolf Ledge Parkway, Akron, OH 44311) V.1- 1981- Volume(issue)/page/year: 6,46,1986 *** END OF RECORD ***