*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : UQ4915500
CHEMICAL NAME           : 1H-Pyrazole-4-acetic acid,
                          3-(4-chlorophenyl)-1-phenyl-, sodium salt
CAS REGISTRY NUMBER     : 98647-62-2
LAST UPDATED            : 199409
DATA ITEMS CITED        : 2
MOLECULAR FORMULA       : C17-H12-Cl-N2-O2.Na
MOLECULAR WEIGHT        : 334.75
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * Lonazolac sodium
   * Sodium 3-(4-chlorophenyl)-1-phenyl-1H-pyrazole-4-acetate
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 177 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   ARZNAD Arzneimittel-Forschung. Drug Research.  (Editio Cantor Verlag,
   Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.)  V.1-    1951-
   Volume(issue)/page/year: 31,655,1981
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 193 mg/kg
TOXIC EFFECTS :
   Behavioral - tremor
   Behavioral - convulsions or effect on seizure threshold
REFERENCE :
   ARZNAD Arzneimittel-Forschung. Drug Research.  (Editio Cantor Verlag,
   Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.)  V.1-    1951-
   Volume(issue)/page/year: 31,655,1981
 
                            *** END OF RECORD ***