*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : UQ8420000
CHEMICAL NAME           : 3,5-Pyrazolidinedione, 4-butyl-1-phenyl-
CAS REGISTRY NUMBER     : 2210-63-1
BEILSTEIN REFERENCE NO. : 0213056
REFERENCE               : 5-24-05-00400 (Beilstein Handbook Reference)
LAST UPDATED            : 199612
DATA ITEMS CITED        : 5
MOLECULAR FORMULA       : C13-H16-N2-O2
MOLECULAR WEIGHT        : 232.31
WISWESSER LINE NOTATION : T5VMNV EHJ CR& E4
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * Arcomonol tablets
   * 4-Butyl-1-phenyl-3,5-dioxopyrazolidine
   * 4-Butyl-1-phenyl-3,5-pyrazolidinedione
   * 2 Fdbp
   * Mobutazon
   * Mobuzon
   * Mofebutazone
   * Monazan
   * Monobutyl
   * Monophenylbutazone
   * Monorheumetten
   * 2-Phenyl-3,5-dihydroxy-4-butylpyrazolidine
   * Reumatox
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 1750 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   PAHEAA Pharmaceutica Acta Helvetiae.  (Schweizerische Apothekerzeitung,
   Postfach 3006, CH3000 Bern, 7, Switzerland)  V.1-    1926-
   Volume(issue)/page/year: 39,155,1964
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 848 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   FRPSAX Farmaco, Edizione Scientifica. (Casella Postale 227, 27100 Pavia,
   Italy)  V.8-43 1953-88 For publisher information, see FRMCE8
   Volume(issue)/page/year: 14,347,1959
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 700 mg/kg
TOXIC EFFECTS :
   Behavioral - tremor
   Behavioral - convulsions or effect on seizure threshold
   Lungs, Thorax, or Respiration - dyspnea
REFERENCE :
   SCPHA4 Scientia Pharmaceutica.  (Oesterreichische
   Apotheker-Verlagsgesellschaft MBH, Spitalgasse 31, 1094 Vienna 9, Austria)
   V.1-    1930-  Volume(issue)/page/year: 37,185,1969
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 920 mg/kg
TOXIC EFFECTS :
   Behavioral - tremor
   Behavioral - convulsions or effect on seizure threshold
   Lungs, Thorax, or Respiration - dyspnea
REFERENCE :
   SCPHA4 Scientia Pharmaceutica.  (Oesterreichische
   Apotheker-Verlagsgesellschaft MBH, Spitalgasse 31, 1094 Vienna 9, Austria)
   V.1-    1930-  Volume(issue)/page/year: 37,185,1969
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 600 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   AEPPAE Naunyn-Schmiedeberg's Archiv fuer Experimentelle Pathologie und
   Pharmakologie.  (Berlin, Ger.) V.110-253, 1925-66.  For publisher
   information, see NSAPCC.  Volume(issue)/page/year: 233,365,1958
 
                            *** END OF RECORD ***