*** CHEMICAL IDENTIFICATION ***
RTECS NUMBER : UQ8455500
CHEMICAL NAME : 3,5-Pyrazolidinedione, 1,4-diphenyl-
CAS REGISTRY NUMBER : 3426-01-5
LAST UPDATED : 199712
DATA ITEMS CITED : 3
MOLECULAR FORMULA : C15-H11-N2-O2
MOLECULAR WEIGHT : 251.28
WISWESSER LINE NOTATION : T5VMNV EHJ CR& ER
COMPOUND DESCRIPTOR : Drug
SYNONYMS/TRADE NAMES :
* Diphenox
* 1,4-Diphenyl-3,5-dioxo-pyrazolidin
* 1,4-Diphenyl-3,5-pyrazolidinedione
* DPHP
* Kr 122
* Phenopyrazone
*** HEALTH HAZARD DATA ***
** ACUTE TOXICITY DATA **
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Oral
SPECIES OBSERVED : Rodent - mouse
DOSE/DURATION : >3200 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
YKKZAJ Yakugaku Zasshi. Journal of Pharmacy. (Nippon Yakugakkai, 2-12-15
Shibuya, Shibuya-ku, Tokyo 150, Japan) No.1- 1881-
Volume(issue)/page/year: 98,679,1978
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Subcutaneous
SPECIES OBSERVED : Rodent - mouse
DOSE/DURATION : 1003 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag,
Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951-
Volume(issue)/page/year: 4,249,1954
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Intravenous
SPECIES OBSERVED : Rodent - mouse
DOSE/DURATION : 740 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
AEPPAE Naunyn-Schmiedeberg's Archiv fuer Experimentelle Pathologie und
Pharmakologie. (Berlin, Ger.) V.110-253, 1925-66. For publisher
information, see NSAPCC. Volume(issue)/page/year: 233,365,1958
*** END OF RECORD ***