*** CHEMICAL IDENTIFICATION *** RTECS NUMBER : UQ9510000 CHEMICAL NAME : 2-Pyrazolin-5-one, 3-methyl-4-nitro-1-(p-nitrophenyl)- CAS REGISTRY NUMBER : 550-74-3 BEILSTEIN REFERENCE NO. : 0623723 LAST UPDATED : 199701 DATA ITEMS CITED : 6 MOLECULAR FORMULA : C10-H8-N4-O5 MOLECULAR WEIGHT : 264.22 WISWESSER LINE NOTATION : T5NNVJ BR DNW& DNW E1 COMPOUND DESCRIPTOR : Mutagen SYNONYMS/TRADE NAMES : * 3-Methyl-4-nitro-1-(p-nitrophenyl)-2-pyrazolin-5-one * Picrolonic acid *** HEALTH HAZARD DATA *** ** ACUTE TOXICITY DATA ** TYPE OF TEST : LD - Lethal dose ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - rat DOSE/DURATION : >500 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : NCNSA6 National Academy of Sciences, National Research Council, Chemical-Biological Coordination Center, Review. (Washington, DC) Volume(issue)/page/year: 5,23,1953 ** MUTATION DATA ** TYPE OF TEST : Mutation in microorganisms TEST SYSTEM : Bacteria - Salmonella typhimurium DOSE/DURATION : 25 ug/plate REFERENCE : MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 28,127,1975 TYPE OF TEST : DNA repair TEST SYSTEM : Bacteria - Escherichia coli DOSE/DURATION : 1 mg/plate REFERENCE : MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 54,101,1978 TYPE OF TEST : Mutation in microorganisms TEST SYSTEM : Mold - Aspergillus nidulans DOSE/DURATION : 250 mg/L REFERENCE : MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 97,293,1982 *** STATUS IN U.S. *** EPA GENETOX PROGRAM 1988, Positive: E coli polA without S9; Histidine reversion-Ames test EPA TSCA Section 8(b) CHEMICAL INVENTORY *** END OF RECORD ***