*** CHEMICAL IDENTIFICATION *** RTECS NUMBER : UR0130000 CHEMICAL NAME : Pyrazolo(5,1-a)isoquinoline-1-methanol, 5,6-dihydro-2-phenyl- CAS REGISTRY NUMBER : 61001-40-9 BEILSTEIN REFERENCE NO. : 0677073 LAST UPDATED : 199612 DATA ITEMS CITED : 2 MOLECULAR FORMULA : C18-H16-N2-O MOLECULAR WEIGHT : 276.36 WISWESSER LINE NOTATION : T B566 ENN&T&J C1Q DR COMPOUND DESCRIPTOR : Reproductive Effector SYNONYMS/TRADE NAMES : * 5,6-Dihydro-2-phenylpyrazolo(5,1-a)isoquinoline-1-methanol * 2-Phenyl-5,6-dihydro-pyrazolo(5,1-a)isoquinoline-1-methanol *** HEALTH HAZARD DATA *** ** REPRODUCTIVE DATA ** TYPE OF TEST : TDLo - Lowest published toxic dose ROUTE OF EXPOSURE : Subcutaneous SPECIES OBSERVED : Rodent - rat DOSE : 100 mg/kg SEX/DURATION : female 6-10 day(s) after conception TOXIC EFFECTS : Reproductive - Fertility - post-implantation mortality (e.g. dead and/or resorbed implants per total number of implants) REFERENCE : EJMCA5 European Journal of Medicinal Chemistry--Chimie Therapeutique. (Editions Scientifiques Elsevier, 29 rue Buffon, F-75005, Paris, France) V.9- 1974- Volume(issue)/page/year: 17,223,1982 TYPE OF TEST : TDLo - Lowest published toxic dose ROUTE OF EXPOSURE : Subcutaneous SPECIES OBSERVED : Rodent - hamster DOSE : 50 mg/kg SEX/DURATION : female 4-8 day(s) after conception TOXIC EFFECTS : Reproductive - Fertility - post-implantation mortality (e.g. dead and/or resorbed implants per total number of implants) REFERENCE : EJMCA5 European Journal of Medicinal Chemistry--Chimie Therapeutique. (Editions Scientifiques Elsevier, 29 rue Buffon, F-75005, Paris, France) V.9- 1974- Volume(issue)/page/year: 17,223,1982 *** END OF RECORD ***