*** CHEMICAL IDENTIFICATION *** RTECS NUMBER : UR0150000 CHEMICAL NAME : Pyrazol-4-ol CAS REGISTRY NUMBER : 4843-98-5 BEILSTEIN REFERENCE NO. : 0106311 REFERENCE : 5-23-10-00487 (Beilstein Handbook Reference) LAST UPDATED : 199612 DATA ITEMS CITED : 2 MOLECULAR FORMULA : C3-H4-N2-O MOLECULAR WEIGHT : 84.09 WISWESSER LINE NOTATION : T5MNJ DQ COMPOUND DESCRIPTOR : Drug SYNONYMS/TRADE NAMES : * 4-HP * 4-Hydroxypyrazole * 1H-Pyrazol-4-ol *** HEALTH HAZARD DATA *** ** ACUTE TOXICITY DATA ** TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intraperitoneal SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 92 mg/kg TOXIC EFFECTS : Liver - hepatitis (hepatocellular necrosis), zonal REFERENCE : APTOA6 Acta Pharmacologica et Toxicologica. (Copenhagen, Denmark) V.1-59, 1945-86. For publisher information, see PHTOEH Volume(issue)/page/year: 48,418,1981 ** OTHER MULTIPLE DOSE TOXICITY DATA ** TYPE OF TEST : TDLo - Lowest published toxic dose ROUTE OF EXPOSURE : Intraperitoneal SPECIES OBSERVED : Rodent - rat DOSE/DURATION : 336 mg/kg/7D-I TOXIC EFFECTS : Biochemical - Enzyme inhibition, induction, or change in blood or tissue levels - other Enzymes Biochemical - Metabolism (Intermediary) - other proteins REFERENCE : APTOA6 Acta Pharmacologica et Toxicologica. (Copenhagen, Denmark) V.1-59, 1945-86. For publisher information, see PHTOEH Volume(issue)/page/year: 48,418,1981 *** END OF RECORD ***