*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : UR0794030
CHEMICAL NAME           : 4H-Pyrazolo(3,4-d)pyrimidin-4-one,
                          1,5-dihydro-5-amino-6-((3-fluorophenyl)amino)-
CAS REGISTRY NUMBER     : 141300-24-5
BEILSTEIN REFERENCE NO. : 4877316
LAST UPDATED            : 199612
DATA ITEMS CITED        : 2
MOLECULAR FORMULA       : C11-H9-F-N6-O
MOLECULAR WEIGHT        : 260.26
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   *   1,5-Dihydro-5-amino-6-((3-fluorophenyl)amino)-4H-pyrazolo(3,4-d)pyrimidi
     n-4-one
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : >1 gm/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   EJMCA5 European Journal of Medicinal Chemistry--Chimie Therapeutique.
   (Editions Scientifiques Elsevier, 29 rue Buffon, F-75005, Paris, France)
   V.9-    1974-  Volume(issue)/page/year: 27,73,1992
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 800 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   EJMCA5 European Journal of Medicinal Chemistry--Chimie Therapeutique.
   (Editions Scientifiques Elsevier, 29 rue Buffon, F-75005, Paris, France)
   V.9-    1974-  Volume(issue)/page/year: 27,73,1992
 
                            *** END OF RECORD ***