*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : UR8420000
CHEMICAL NAME           : 2-Pyridineacetamide,
                          alpha-(2-(bis(1-methylethyl)amino)ethyl)-alpha-phenyl
                          -, monohydrochloride
CAS REGISTRY NUMBER     : 54687-36-4
LAST UPDATED            : 198812
DATA ITEMS CITED        : 2
MOLECULAR FORMULA       : C21-H29-N3-O.Cl-H
MOLECULAR WEIGHT        : 375.99
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * alpha-(2-(Bis(1-methylethyl)amino)ethyl)-alpha-phenyl-2-pyridineacetamide 
    hydrochloride
   * Disopyramide hydrochloride
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 51 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   JNPHAG Journal de Pharmacologie.  (SPPIF, B.P.22, F-41353 Vineuil, France)
   V.1-    1970-  Volume(issue)/page/year: 5,101,1974
 
TYPE OF TEST            : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Mammal - dog
DOSE/DURATION           : 37 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   JNPHAG Journal de Pharmacologie.  (SPPIF, B.P.22, F-41353 Vineuil, France)
   V.1-    1970-  Volume(issue)/page/year: 2,240,1971
 
                            *** END OF RECORD ***