*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : UR8750000
CHEMICAL NAME           : 1(4H)-Pyridineacetic acid, 3,5-diiodo-4-oxo-, compd.
                          with 2,2'-iminodiethanol (1:1)
CAS REGISTRY NUMBER     : 300-37-8
LAST UPDATED            : 199512
DATA ITEMS CITED        : 5
MOLECULAR FORMULA       : C7-H5-I2-N-O3.C4-H11-N-O2
MOLECULAR WEIGHT        : 510.09
WISWESSER LINE NOTATION : T6N DVJ A1VQ CI EI
SYNONYMS/TRADE NAMES :
   * Bis(hydroxyethyl)ammonium 3,5-diiodo-4-pyridone-N-acetate
   * Cardiotrast
   * Diaethanolamin. 3,5-dijodpyridon-(4)-essigsaeure
   * Diatrast
   * Diethanolamine 3,5-diiodo-4-pyridone-N-acetate
   * 3,5-Diiodo-4-oxo-1(4H)pyridineacetic acid 2,2'-iminodiethanol salt
   * 3,5-Diiodo-4-pyridone-N-acetic acid, diethanolamine salt
   * Diodon
   * Diodone
   * Diodrast
   * Ethanol, 2,2'-iminodi-, 3,5-diiodo-4-oxo-1(4H)-pyridineacetate (salt)
   * Ethanol, 2,2'-iminodi-, compd. with 3,5-diiodo-4-oxo-1(4H)-pyridineacetic 
    acid (1:1)
   * Iodopyracet
   * Ioduron B
   * Iopyracil
   * Methylglucamine 3,5-diiodo-4-pyridone N-acetate
   * Neomethiodal
   * Nosylan
   * Neo-skiodan
   * Neo-tenebryl
   * Nosydrast
   * Oparenol
   * Pelviran
   * Per-Abrodil
   * Per-Radiographol
   * Pyelosil
   * Pylumbrin
   * Pyraceton
   * RP 3203
   * Savac
   * Umbradil
   * Uriodone
   * Vasiodone
   * Xumbradil
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 5400 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   AEPPAE Naunyn-Schmiedeberg's Archiv fuer Experimentelle Pathologie und
   Pharmakologie.  (Berlin, Ger.) V.110-253, 1925-66.  For publisher
   information, see NSAPCC.  Volume(issue)/page/year: 222,584,1954
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 6400 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   JPETAB Journal of Pharmacology and Experimental Therapeutics.  (Williams &
   Wilkins Co., 428 E. Preston St., Baltimore, MD 21202)  V.1-    1909/10-
   Volume(issue)/page/year: 116,394,1956
 
TYPE OF TEST            : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Mammal - dog
DOSE/DURATION           : 2 gm/kg
TOXIC EFFECTS :
   Lungs, Thorax, or Respiration - other changes
REFERENCE :
   BJRAAP British Journal of Radiology.  (British Institute of Radiology, 36
   Portland Pl., London, UK) V.1-    1928-  Volume(issue)/page/year: 6,304,1933
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Mammal - cat
DOSE/DURATION           : 2800 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   MECHAN Medicinal Chemistry, A Series of Reviews.  (New York, NY)  V.1-6,
   1951-63.  Discontinued.  Volume(issue)/page/year: 6,344,1963
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - rabbit
DOSE/DURATION           : 4700 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   MECHAN Medicinal Chemistry, A Series of Reviews.  (New York, NY)  V.1-6,
   1951-63.  Discontinued.  Volume(issue)/page/year: 6,344,1963
 
                            *** END OF RECORD ***