*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : UR8925000
CHEMICAL NAME           : 1(4H)-Pyridineacetic acid, 3,5-diiodo-4-oxo-, propyl
                          ester
CAS REGISTRY NUMBER     : 587-61-1
BEILSTEIN REFERENCE NO. : 0206829
REFERENCE               : 5-21-07-00164 (Beilstein Handbook Reference)
LAST UPDATED            : 199612
DATA ITEMS CITED        : 3
MOLECULAR FORMULA       : C10-H11-I2-N-O3
MOLECULAR WEIGHT        : 447.02
WISWESSER LINE NOTATION : T6N DVJ A1VO3 CI EI
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * A.G. 33-107
   * Bronchodiagnostin
   * Brosombra
   * 3,5-Diiodo-4-oxo-1(4H)-pyridineacetic acid propyl ester
   * 3,5-Diiodo-4-pyridone-N-acetic acid propyl ester
   * Dionosil
   * Diostril
   * Propiodone
   * Propyl-3,5-diiodo-4-oxo-1(4H)pyridineacetate
   * Propyl 3,5-diiodo-4-pyridone-N-acetate
   * Propyliodone
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : >18 gm/kg
TOXIC EFFECTS :
   Kidney, Ureter, Bladder - other changes
REFERENCE :
   BJPCAL British Journal of Pharmacology and Chemotherapy.  (London, UK)
   V.1-33, 1946-68.  For publisher information, see BJPCBM.
   Volume(issue)/page/year: 8,166,1953
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 300 mg/kg
TOXIC EFFECTS :
   Vascular - acute arterial occlusion
REFERENCE :
   BJPCAL British Journal of Pharmacology and Chemotherapy.  (London, UK)
   V.1-33, 1946-68.  For publisher information, see BJPCBM.
   Volume(issue)/page/year: 8,166,1953
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Unreported
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 300 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   YAKUD5 Gekkan Yakuji.  Pharmaceuticals Monthly.  (Yakugyo Jihosha, Inaoka
   Bldg., 2-36 Jinbo-cho, Kanda, Chiyoda-ku, Tokyo 101, Japan)  V.1-   1959-
   Volume(issue)/page/year: 26,921,1984
 
                            *** END OF RECORD ***