*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : US4587000
CHEMICAL NAME           : 4-Pyridinecarboxamide,
                          N-((1-butyl-4-phenyl-4-piperidinyl)methyl)-
CAS REGISTRY NUMBER     : 59455-24-2
BEILSTEIN REFERENCE NO. : 0449679
LAST UPDATED            : 199612
DATA ITEMS CITED        : 2
MOLECULAR FORMULA       : C22-H29-N3-O
MOLECULAR WEIGHT        : 351.54
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * BG 25
   * 1-Butyl-4-phenyl-4-isonicotinoylaminomethylpiperidine
   * N-((1-Butyl-4-phenyl-4-piperidinyl)methyl)-4-pyridinecarboxamide
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 125 mg/kg
TOXIC EFFECTS :
   Behavioral - convulsions or effect on seizure threshold
   Behavioral - analgesia
REFERENCE :
   PJPPAA Polish Journal of Pharmacology and Pharmacy.  (ARS Polona, POB 1001,
   00-068 Warsaw 1, Poland) V.25-    1973-  Volume(issue)/page/year:
   32,141,1980
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 360 mg/kg
TOXIC EFFECTS :
   Behavioral - convulsions or effect on seizure threshold
   Behavioral - analgesia
REFERENCE :
   PJPPAA Polish Journal of Pharmacology and Pharmacy.  (ARS Polona, POB 1001,
   00-068 Warsaw 1, Poland) V.25-    1973-  Volume(issue)/page/year:
   32,141,1980
 
                            *** END OF RECORD ***