*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : US4667260
CHEMICAL NAME           : 4-Pyridinecarboxamide,
                          N-(2-((8-beta)-6-methylergolin-8-yl)ethyl)-,
                          (R-(R*,R*))-2,3- dihydroxybutanedioate
LAST UPDATED            : 198910
DATA ITEMS CITED        : 1
MOLECULAR FORMULA       : C23-H26-N4-O.C4-H6-O6
MOLECULAR WEIGHT        : 524.63
COMPOUND DESCRIPTOR     : Reproductive Effector
SYNONYMS/TRADE NAMES :
   * N-(2-((8-beta)-6-Methylergolin-8-yl)ethyl)-4-pyridinecarboxamide tartrate
 
                       *** HEALTH HAZARD DATA ***
 
                          ** REPRODUCTIVE DATA **
 
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE                    : 2500 ug/kg
SEX/DURATION            : female 1-6 day(s) after conception
TOXIC EFFECTS :
   Reproductive - Fertility - pre-implantation mortality (e.g. reduction in
   number of implants per female; total number of implants per corpora lutea)
REFERENCE :
   CCCCAK Collection of Czechoslovak Chemical Communications.  (Academic Press
   Inc. Ltd., 24-28 Oval Rd., London NW1 7DX, UK)  V.1-    1929-
   Volume(issue)/page/year: 41,1042,1976
 
                            *** END OF RECORD ***