*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : US5635000
CHEMICAL NAME           : 4-Pyridinecarboxylic acid,
                          (1-carboxyethylidene)hydrazine, calcium salt (2:1)
CAS REGISTRY NUMBER     : 3428-05-5
LAST UPDATED            : 199712
DATA ITEMS CITED        : 2
MOLECULAR FORMULA       : C18-H16-N6-O6.Ca
MOLECULAR WEIGHT        : 452.48
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * Isoniazid calcium pyruvate
   * Isonicotinic acid, (1-carboxyethylidene)hydrazide, calcium salt (2:1)
   * Pyruvic acid calcium isoniazone
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : >800 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   NIIRDN Drugs in Japan (Ethical Drugs).  (Yakugyo Jiho Co., Ltd., Tokyo,
   Japan)  Volume(issue)/page/year: -,117,1990
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 1231 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   NIIRDN Drugs in Japan (Ethical Drugs).  (Yakugyo Jiho Co., Ltd., Tokyo,
   Japan)  Volume(issue)/page/year: -,117,1990
 
                            *** END OF RECORD ***