*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : US5646070
CHEMICAL NAME           : 3-Pyridinecarboxylic acid,
                          2-(2-(4-chlorophenoxy)-2-methyl-1-oxopropoxy)-1,3-pro
                          panediyl ester
CAS REGISTRY NUMBER     : 69047-39-8
LAST UPDATED            : 199109
DATA ITEMS CITED        : 4
MOLECULAR FORMULA       : C25-H23-Cl-N2-O7
MOLECULAR WEIGHT        : 498.95
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * Binifibrate
   * Biniwas
   * Glyceryl 2-p-chlorophenoxyisobutyrate-1,3-dinicotinate
   * Trihydroxypropane 2-p-chlorophenoxyisobutyrate-1,3-dinicotinate
   * WAC 104
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : >4 gm/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   MEIEDD Merck Index. (Merck & Co., Inc., Rahway, NJ 07065)  10th ed. 1983.
   For publisher information, see 85KYAH.  Volume(issue)/page/year: 11,191,1989
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : >4 gm/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   DRFUD4 Drugs of the Future.  (J.R. Prous, S.A., Apartado de Correos 540,
   08080 Barcelona, Spain) V.1-    1975/76-  Volume(issue)/page/year:
   4,681,1979
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : >4 gm/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   MEIEDD Merck Index. (Merck & Co., Inc., Rahway, NJ 07065)  10th ed. 1983.
   For publisher information, see 85KYAH.  Volume(issue)/page/year: 11,191,1989
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 3100 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   DRFUD4 Drugs of the Future.  (J.R. Prous, S.A., Apartado de Correos 540,
   08080 Barcelona, Spain) V.1-    1975/76-  Volume(issue)/page/year:
   4,681,1979
 
                            *** END OF RECORD ***