*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : US5908280
CHEMICAL NAME           : 4-Pyridinecarboxylic acid, 2-(sulfomethyl)hydrazide,
                          compd. with (S-(R*,R*))-2,2'-(1,2-
                          ethanediyldiimino)bis(1-butanol) (2:1)
CAS REGISTRY NUMBER     : 41663-50-7
LAST UPDATED            : 199009
DATA ITEMS CITED        : 2
MOLECULAR FORMULA       : C10-H24-N2-O2.2C7-H9-N3-O4-S
MOLECULAR WEIGHT        : 666.86
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * Di-isoniazidmethane sulfonate of d(+)2,2'(ethylenediimino)di-1-butanol
   * Ethambutol isoniazid methanesulfonate
   * Isobutol
   * Isoetam
   * Isoetham
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 2800 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   USXXAM United States Patent Document.  (U.S. Patent Office, Box 9,
   Washington, DC 20231)  Volume(issue)/page/year: #3718655
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 2210 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   USXXAM United States Patent Document.  (U.S. Patent Office, Box 9,
   Washington, DC 20231)  Volume(issue)/page/year: #3718655
 
                            *** END OF RECORD ***