*** CHEMICAL IDENTIFICATION *** RTECS NUMBER : US7370000 CHEMICAL NAME : Pyridine, 2-((5-chloro-2-thenyl)(2-(dimethylamino)ethyl)amino)- , hydrochloride CAS REGISTRY NUMBER : 135-35-3 LAST UPDATED : 198708 DATA ITEMS CITED : 3 MOLECULAR FORMULA : C14-H18-Cl-N3-S.Cl-H MOLECULAR WEIGHT : 332.32 COMPOUND DESCRIPTOR : Drug SYNONYMS/TRADE NAMES : * Chlorothen hydrochloride * N,N-Dimethyl-N'-(2-pyridyl)-N'-(5-chloro-2-thenyl)ethylenediamine hydrochloride * Thenchlor *** HEALTH HAZARD DATA *** ** ACUTE TOXICITY DATA ** TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 438 mg/kg TOXIC EFFECTS : Behavioral - excitement Behavioral - muscle contraction or spasticity Lungs, Thorax, or Respiration - dyspnea REFERENCE : JHHBAI Bulletin of the Johns Hopkins Hospital. (Baltimore, MD) V.1-119, 1889-1966. For publisher information, see JHMJAX. Volume(issue)/page/year: 81,55,1947 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intraperitoneal SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 126 mg/kg TOXIC EFFECTS : Behavioral - excitement Behavioral - muscle contraction or spasticity Lungs, Thorax, or Respiration - dyspnea REFERENCE : JHHBAI Bulletin of the Johns Hopkins Hospital. (Baltimore, MD) V.1-119, 1889-1966. For publisher information, see JHMJAX. Volume(issue)/page/year: 81,55,1947 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intravenous SPECIES OBSERVED : Rodent - rabbit DOSE/DURATION : 86500 ug/kg TOXIC EFFECTS : Behavioral - excitement Behavioral - muscle contraction or spasticity Lungs, Thorax, or Respiration - dyspnea REFERENCE : JHHBAI Bulletin of the Johns Hopkins Hospital. (Baltimore, MD) V.1-119, 1889-1966. For publisher information, see JHMJAX. Volume(issue)/page/year: 81,55,1947 *** END OF RECORD ***