*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : US7970000
CHEMICAL NAME           : 2,6-Pyridinedicarboxylic acid,
                          1,4-dihydro-3,5-diiodo-1-methyl-4-oxo-, disodium salt
CAS REGISTRY NUMBER     : 519-26-6
LAST UPDATED            : 199707
DATA ITEMS CITED        : 5
MOLECULAR FORMULA       : C8-H-I2-N-O5.2Na
MOLECULAR WEIGHT        : 490.88
WISWESSER LINE NOTATION : T6N DVJ A1 BVO CI EI FVO &-NA- 2
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * Chelidamic acid, 3,5-diiodo-1-methyl-, disodium salt
   * 1,4-Dihydro-3,5-diiodo-1-methyl-4-oxo-2,6-pyridinedicarboxylic acid  
   disodium salt
   * D 40
   * 3,5-Diiodo-1-methylchelidamic acid sodium salt
   * 3,5-Dijod-4-pyridoxyl-N-methyl-2,6-dicarbonsaeure natrium
   * Disodium 1,4-dihydro-3,5-diiodo-1-methyl-4-oxo-2,6-pyridinedicarboxylate
   * Disodium N-methyl-3,5-diiodo-4-pyridone-2,6-dicarboxylate
   * Iodomethamate sodium
   * Iodoxyl
   * neo-Iopax
   * neo-Iopax R
   * neo-Iopax sodium
   * Sodium iodomethamate
   * Ultraren sodium
   * Uropac
   * Uroselectan B
   * Urotrast
   * Urumbrin
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 6800 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   JPETAB Journal of Pharmacology and Experimental Therapeutics.  (Williams &
   Wilkins Co., 428 E. Preston St., Baltimore, MD 21202)  V.1-    1909/10-
   Volume(issue)/page/year: 116,394,1956
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 4 gm/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   JPETAB Journal of Pharmacology and Experimental Therapeutics.  (Williams &
   Wilkins Co., 428 E. Preston St., Baltimore, MD 21202)  V.1-    1909/10-
   Volume(issue)/page/year: 116,394,1956
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Mammal - dog
DOSE/DURATION           : 7130 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   MECHAN Medicinal Chemistry, A Series of Reviews.  (New York, NY)  V.1-6,
   1951-63.  Discontinued.  Volume(issue)/page/year: 6,344,1963
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Mammal - cat
DOSE/DURATION           : 6300 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   MECHAN Medicinal Chemistry, A Series of Reviews.  (New York, NY)  V.1-6,
   1951-63.  Discontinued.  Volume(issue)/page/year: 6,344,1963
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - rabbit
DOSE/DURATION           : 5100 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   MECHAN Medicinal Chemistry, A Series of Reviews.  (New York, NY)  V.1-6,
   1951-63.  Discontinued.  Volume(issue)/page/year: 6,344,1963
 
                            *** END OF RECORD ***