*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : UT2810530
CHEMICAL NAME           : 2,4(1H,3H)-Pyridinedione, 3,3-diethyl-
CAS REGISTRY NUMBER     : 77-04-3
BEILSTEIN REFERENCE NO. : 0131564
REFERENCE               : 5-21-10-00086 (Beilstein Handbook Reference)
LAST UPDATED            : 199612
DATA ITEMS CITED        : 3
MOLECULAR FORMULA       : C9-H13-N-O2
MOLECULAR WEIGHT        : 167.23
WISWESSER LINE NOTATION : T6MV DV CHJ C2 C2
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * Benedorm
   * Didropyridine
   * 3,3-Diethyl-2,4-pyridinedione
   * 3,3-Diethyl-2,4(1H,3H)-pyridinedione
   * Dihydroprylone
   * NU 903
   * Persedon
   * Presidon
   * Pyridion
   * Pyridione
   * Pyrithyldion
   * Pyrithyldione
   * Tetridin
   * Tetridine
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 780 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   APPBDI Acta Physiologica et Pharmacologica Bulgarica.  (Izdatelstvo na
   Bulgarskata Akademiya na Naukite, ul. Akad. G. Bonchev, 1113 Sofia,
   Bulgaria)  V.1-    1974-  Volume(issue)/page/year: 10(3),29,1984
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 660 mg/kg
TOXIC EFFECTS :
   Behavioral - anticonvulsant
   Behavioral - sleep
   Behavioral - changes in motor activity (specific assay)
REFERENCE :
   DBANAD Doklady Bolgarskoi Akademii Nauk.  (Hemus, Blvd. Russki 6, Sofia,
   Bulgaria)  V.1-    1948-  Volume(issue)/page/year: 34,135,1981
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 980 mg/kg
TOXIC EFFECTS :
   Behavioral - anticonvulsant
   Behavioral - sleep
   Behavioral - changes in motor activity (specific assay)
REFERENCE :
   DBANAD Doklady Bolgarskoi Akademii Nauk.  (Hemus, Blvd. Russki 6, Sofia,
   Bulgaria)  V.1-    1948-  Volume(issue)/page/year: 34,135,1981
 
                            *** END OF RECORD ***