*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : UT5009000
CHEMICAL NAME           : 3-Pyridinemethanol,
                          5-hydroxy-4-(methoxymethyl)-6-methyl-
CAS REGISTRY NUMBER     : 1464-33-1
BEILSTEIN REFERENCE NO. : 0150788
REFERENCE               : 5-21-05-00494 (Beilstein Handbook Reference)
LAST UPDATED            : 199612
DATA ITEMS CITED        : 7
MOLECULAR FORMULA       : C9-H13-N-O3
MOLECULAR WEIGHT        : 183.23
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * 5-Hydroxy-4-(methoxymethyl)-6-methyl-3-pyridinemethanol
   * 4-Methoxypyridoxine
   * alpha(sup 4)-O-Methylpyridoxol
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 540 mg/kg
TOXIC EFFECTS :
   Behavioral - somnolence (general depressed activity)
   Behavioral - convulsions or effect on seizure threshold
   Lungs, Thorax, or Respiration - dyspnea
REFERENCE :
   PSDTAP Proceedings of the European Society for the Study of Drug Toxicity.
   (Princeton, NJ 08540) V.1-15, 1963-74.  For publisher information, see
   PESTD5.  Volume(issue)/page/year: 4,179,1964
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 32 mg/kg
TOXIC EFFECTS :
   Behavioral - convulsions or effect on seizure threshold
REFERENCE :
   PSDTAP Proceedings of the European Society for the Study of Drug Toxicity.
   (Princeton, NJ 08540) V.1-15, 1963-74.  For publisher information, see
   PESTD5.  Volume(issue)/page/year: 4,179,1964
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 23 mg/kg
TOXIC EFFECTS :
   Behavioral - convulsions or effect on seizure threshold
REFERENCE :
   PSDTAP Proceedings of the European Society for the Study of Drug Toxicity.
   (Princeton, NJ 08540) V.1-15, 1963-74.  For publisher information, see
   PESTD5.  Volume(issue)/page/year: 4,179,1964
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 20 mg/kg
TOXIC EFFECTS :
   Behavioral - convulsions or effect on seizure threshold
REFERENCE :
   PSDTAP Proceedings of the European Society for the Study of Drug Toxicity.
   (Princeton, NJ 08540) V.1-15, 1963-74.  For publisher information, see
   PESTD5.  Volume(issue)/page/year: 4,179,1964
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Mammal - dog
DOSE/DURATION           : 8 mg/kg
TOXIC EFFECTS :
   Behavioral - convulsions or effect on seizure threshold
   Lungs, Thorax, or Respiration - respiratory depression
REFERENCE :
   PSDTAP Proceedings of the European Society for the Study of Drug Toxicity.
   (Princeton, NJ 08540) V.1-15, 1963-74.  For publisher information, see
   PESTD5.  Volume(issue)/page/year: 4,179,1964
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Mammal - cat
DOSE/DURATION           : 9 mg/kg
TOXIC EFFECTS :
   Behavioral - convulsions or effect on seizure threshold
   Lungs, Thorax, or Respiration - respiratory depression
REFERENCE :
   PSDTAP Proceedings of the European Society for the Study of Drug Toxicity.
   (Princeton, NJ 08540) V.1-15, 1963-74.  For publisher information, see
   PESTD5.  Volume(issue)/page/year: 4,179,1964
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - rabbit
DOSE/DURATION           : 17 mg/kg
TOXIC EFFECTS :
   Behavioral - convulsions or effect on seizure threshold
   Lungs, Thorax, or Respiration - respiratory depression
REFERENCE :
   PSDTAP Proceedings of the European Society for the Study of Drug Toxicity.
   (Princeton, NJ 08540) V.1-15, 1963-74.  For publisher information, see
   PESTD5.  Volume(issue)/page/year: 4,179,1964
 
                            *** END OF RECORD ***