*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : UT6130000
CHEMICAL NAME           : Pyridine, 3-(1-methyl-2-pyrrolyl)-
CAS REGISTRY NUMBER     : 487-19-4
BEILSTEIN REFERENCE NO. : 0121347
REFERENCE               : 5-23-07-00227 (Beilstein Handbook Reference)
LAST UPDATED            : 199612
DATA ITEMS CITED        : 3
MOLECULAR FORMULA       : C10-H10-N2
MOLECULAR WEIGHT        : 158.22
WISWESSER LINE NOTATION : T6NJ C- BT5NJ A1
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * 1-Methyl-2-(3-pyridyl)pyrrole
   * 3-(1-Methyl-2-pyrrolyl)pyridine
   * 3-(1-Methyl-1H-pyrrol-2-yl)pyridine
   * Nicotyrine
   * beta-Nicotyrine
   * 3,2'-Nicotyrine
   * Pyridine, 3-(1-methyl-1H-pyrrol-2-yl)-
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 750 mg/kg
TOXIC EFFECTS :
   Behavioral - muscle weakness
   Lungs, Thorax, or Respiration - respiratory depression
REFERENCE :
   USXXAM United States Patent Document.  (U.S. Patent Office, Box 9,
   Washington, DC 20231)  Volume(issue)/page/year: #4065561
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 575 mg/kg
TOXIC EFFECTS :
   Behavioral - altered sleep time (including change in righting reflex)
   Behavioral - somnolence (general depressed activity)
   Behavioral - muscle weakness
REFERENCE :
   USXXAM United States Patent Document.  (U.S. Patent Office, Box 9,
   Washington, DC 20231)  Volume(issue)/page/year: #4065561
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 191 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   TXAPA9 Toxicology and Applied Pharmacology.  (Academic Press, Inc., 1 E.
   First St., Duluth, MN 55802) V.1-    1959-  Volume(issue)/page/year:
   65,366,1982
 
                            *** END OF RECORD ***