*** CHEMICAL IDENTIFICATION *** RTECS NUMBER : UT6386500 CHEMICAL NAME : Pyridine, 4-nitrosomethylamino- CAS REGISTRY NUMBER : 16219-99-1 BEILSTEIN REFERENCE NO. : 0472145 REFERENCE : 5-22-14-00724 (Beilstein Handbook Reference) LAST UPDATED : 199612 DATA ITEMS CITED : 2 MOLECULAR FORMULA : C6-H7-N3-O MOLECULAR WEIGHT : 137.16 WISWESSER LINE NOTATION : T6NJ DN1&NO COMPOUND DESCRIPTOR : Mutagen SYNONYMS/TRADE NAMES : * N-Methyl-N-nitroso-4-aminopyridine * N-Nitroso-N-methyl-4-aminopyridine * 4-Nitrosomethylaminopyridine * Pyridine, 4-(methylnitrosamino)- *** HEALTH HAZARD DATA *** ** ACUTE TOXICITY DATA ** TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - rat DOSE/DURATION : 200 mg/kg TOXIC EFFECTS : Lungs, Thorax, or Respiration - acute pulmonary edema Gastrointestinal - ulceration or bleeding from stomach Gastrointestinal - changes in structure or function of esophagus REFERENCE : JJIND8 JNCI, Journal of the National Cancer Institute. (Washington, DC) V.61-79, 1978-87. For publisher information, see JNCIEQ. Volume(issue)/page/year: 62,153,1979 ** MUTATION DATA ** TYPE OF TEST : Mutation in microorganisms TEST SYSTEM : Bacteria - Salmonella typhimurium DOSE/DURATION : 5 mmol/L REFERENCE : CRNGDP Carcinogenesis (London). (Oxford Univ. Press, Pinkhill House, Southfield Road, Eynsham, Oxford OX8 1JJ, UK) V.1- 1980- Volume(issue)/page/year: 3,415,1982 *** END OF RECORD ***