*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : UU6850000
CHEMICAL NAME           : Pyridinium, 1,1'-(oxydimethylene)bis(4-formyl-,
                          dioxime
CAS REGISTRY NUMBER     : 7683-36-5
LAST UPDATED            : 198910
DATA ITEMS CITED        : 2
MOLECULAR FORMULA       : C14-H16-N4-O3
MOLECULAR WEIGHT        : 288.34
WISWESSER LINE NOTATION : T6KJ D1UNQ A1O1- AT6KJ D1UNQ
COMPOUND DESCRIPTOR     : Human
SYNONYMS/TRADE NAMES :
   * Obidoxim
   * Obidoxime
   * Obidoxime tablets
   * Toxogonin
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Human
DOSE/DURATION           : 39 mg/kg
TOXIC EFFECTS :
   Peripheral Nerve and Sensation - paresthesis
   Behavioral - muscle weakness
   Gastrointestinal - nausea or vomiting
REFERENCE :
   ARTODN Archives of Toxicology.  (Springer-Verlag, Heidelberger Pl. 3, D-1000
   Berlin 33, Fed. Rep. Ger.)  V.32-    1974-  Volume(issue)/page/year:
   36,83,1976
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 203 mg/kg
TOXIC EFFECTS :
   Peripheral Nerve and Sensation - flaccid paralysis without anesthesia
   (usually neuromuscular blockage)
   Biochemical - Enzyme inhibition, induction, or change in blood or tissue
   levels - true cholinesterase
REFERENCE :
   TXAPA9 Toxicology and Applied Pharmacology.  (Academic Press, Inc., 1 E.
   First St., Duluth, MN 55802) V.1-    1959-  Volume(issue)/page/year:
   46,429,1978
 
                            *** END OF RECORD ***