*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : UU8810000
CHEMICAL NAME           : 10H-Pyrido(3,2-b)(1,4)benzothiazine,
                          10-(2-(1-pyrrolidinyl)propyl)-
CAS REGISTRY NUMBER     : 67466-10-8
LAST UPDATED            : 199803
DATA ITEMS CITED        : 2
MOLECULAR FORMULA       : C18-H21-N3-S
MOLECULAR WEIGHT        : 311.48
WISWESSER LINE NOTATION : T C666 BN DN ISJ B1Y1&- AT5NTJ
SYNONYMS/TRADE NAMES :
   * D 264
   * 10-(2-(1-Pyrrolidinyl)propyl)-10H-pyrido(3,2-b)(1,4)benzothiazine
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 135 mg/kg
TOXIC EFFECTS :
   Behavioral - somnolence (general depressed activity)
REFERENCE :
   ARZNAD Arzneimittel-Forschung. Drug Research.  (Editio Cantor Verlag,
   Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.)  V.1-    1951-
   Volume(issue)/page/year: 8,489,1958
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 65 mg/kg
TOXIC EFFECTS :
   Behavioral - somnolence (general depressed activity)
REFERENCE :
   ARZNAD Arzneimittel-Forschung. Drug Research.  (Editio Cantor Verlag,
   Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.)  V.1-    1951-
   Volume(issue)/page/year: 8,489,1958
 
                            *** END OF RECORD ***