*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : UU8817000
CHEMICAL NAME           : 6H-Pyrido(4,3-b)carbazole,
                          1-((2-aminoethyl)amino)-9-methoxy-5-methyl-,
                          hemihydrate
CAS REGISTRY NUMBER     : 74861-67-9
LAST UPDATED            : 198609
DATA ITEMS CITED        : 1
MOLECULAR FORMULA       : C19-H20-N4-O.1/2H2-O
MOLECULAR WEIGHT        : 329.44
WISWESSER LINE NOTATION : T D6 B656 FN LMJ EM2Z J1 PO1 &QH 1/2
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * 1-((2-Aminoethyl)amino)-9-methoxy-5-methyl-6H-pyrido(4,3-b)carbazole  
   hemihydrate
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 10 mg/kg
TOXIC EFFECTS :
   Tumorigenic - active as anti-cancer agent
   Biochemical - Metabolism (Intermediary) - effect on inflammation or
   mediation of inflammation
REFERENCE :
   JMCMAR Journal of Medicinal Chemistry.  (American Chemical Soc.,
   Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC
   20037)  V.6-    1963-  Volume(issue)/page/year: 23,1212,1980
 
                            *** END OF RECORD ***