*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : UU9800000
CHEMICAL NAME           : 3H-Pyrido(3,4-b)indole,
                          4,9-dihydro-7-methoxy-1-methyl-
CAS REGISTRY NUMBER     : 304-21-2
BEILSTEIN REFERENCE NO. : 0207310
REFERENCE               : 5-23-12-00148 (Beilstein Handbook Reference)
LAST UPDATED            : 199612
DATA ITEMS CITED        : 5
MOLECULAR FORMULA       : C13-H14-N2-O
MOLECULAR WEIGHT        : 214.29
WISWESSER LINE NOTATION : T B656 DM HM CHJ F1 KO1
SYNONYMS/TRADE NAMES :
   * Armalin
   * Dihydroharmine
   * 3,4-Dihydroharmine
   * 3,4-Dihydro-7-methoxy-1-methyl-9-pyrido(3,4-b)indole
   * 4,9-Dihydro-7-methoxy-1-methyl-3H-pyrido(3,4-b)indole
   * Harmaline
   * Harmidine
   * Harmine, dihydro-
   * Harmalol methyl ether
   * O-Methylharmalol
   * 1-Methyl-7-methoxy-3,4-dihydro-beta-carboline
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 120 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   VHTODE Veterinary and Human Toxicology.  (American College of Veterinary and
   Comparative Toxicology, Publication Office, Comparative Toxicology,
   Manhattan, KS 66506)  V.19-    1977-  Volume(issue)/page/year: 33,276,1991
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 120 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   PSCBAY Psychopharmacology Service Center, Bulletin.  (Bethesda, MD)  V.1-3,
   1961-65.  For publisher information, see PSYBB9.  Volume(issue)/page/year:
   2,17,1963
 
TYPE OF TEST            : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - rabbit
DOSE/DURATION           : 20 mg/kg
TOXIC EFFECTS :
   Sense Organs and Special Senses (Eye) - mydriasis (pupillary dilation)
   Behavioral - excitement
   Behavioral - ataxia
REFERENCE :
   NEPHBW Neuropharmacology.  (Pergamon Press Ltd., Headington Hill Hall,
   Oxford OX3 OBW, UK) V.9-    1970-  Volume(issue)/page/year: 10,15,1971

                              *** REVIEWS ***
 
   TOXICOLOGY REVIEW
   PISDDJ Pacific Information Service on Street Drugs.  (J.K. Brown, School of
   Pharmacy, Univ. of the Pacific, Stockton, CA 95211)  V.1-    1972(?)-
   Volume(issue)/page/year: 5(3-6),-,1977

   TOXICOLOGY REVIEW
   CTOXAO Clinical Toxicology.  (New York, NY)  V.1-18, 1968-81.  For publisher
   information, see JTCTDW.  Volume(issue)/page/year: 12,1,1978

 
                            *** END OF RECORD ***