*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : UU9865500
CHEMICAL NAME           : 9H-Pyrido(3,4-b)indole, 1,9-dimethyl-7-methoxy-,
                          hydrochloride
LAST UPDATED            : 198603
DATA ITEMS CITED        : 3
MOLECULAR FORMULA       : C14-H14-N2-O.Cl-H
MOLECULAR WEIGHT        : 262.76
WISWESSER LINE NOTATION : T B656 EN HNJ F1 H1 KO1
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * 1,9-Dimethyl-7-methoxy-9H-pyrido(3,4-b)indole hydrochloride
   * Indol-N-methylharmine hydrochloride
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 64 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   QJPPAL Quarterly Journal of Pharmacy & Pharmacology.  (London, UK)  V.2-21,
   1929-48.  For publisher information, see JPPMAB.  Volume(issue)/page/year:
   9,37,1936
 
TYPE OF TEST            : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - guinea pig
DOSE/DURATION           : 38 mg/kg
TOXIC EFFECTS :
   Behavioral - convulsions or effect on seizure threshold
   Behavioral - muscle weakness
   Behavioral - rigidity (including catalepsy)
REFERENCE :
   QJPPAL Quarterly Journal of Pharmacy & Pharmacology.  (London, UK)  V.2-21,
   1929-48.  For publisher information, see JPPMAB.  Volume(issue)/page/year:
   9,37,1936
 
TYPE OF TEST            : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Amphibian - frog
DOSE/DURATION           : 113 mg/kg
TOXIC EFFECTS :
   Behavioral - rigidity (including catalepsy)
   Lungs, Thorax, or Respiration - respiratory depression
REFERENCE :
   QJPPAL Quarterly Journal of Pharmacy & Pharmacology.  (London, UK)  V.2-21,
   1929-48.  For publisher information, see JPPMAB.  Volume(issue)/page/year:
   9,37,1936
 
                            *** END OF RECORD ***