*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : UV0364200
CHEMICAL NAME           : 9H-Pyrido(3,4-b)indole,
                          4a,4b,5,6,7,8,8a,9a-octahydro-7-butoxy-1-methyl-,
                          hydrochloride
LAST UPDATED            : 198608
DATA ITEMS CITED        : 2
MOLECULAR FORMULA       : C16-H24-N2-O.Cl-H
MOLECULAR WEIGHT        : 296.88
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * 7-Butoxy-1-methyl-4a,4b,5,6,7,8,8a,9a-octahydro-9H-pyrido(3,4-b)indole  
   hydrochloride
   * Butyl-harmol hydrochloride
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 330 mg/kg
TOXIC EFFECTS :
   Behavioral - tremor
   Behavioral - convulsions or effect on seizure threshold
   Behavioral - ataxia
REFERENCE :
   QJPPAL Quarterly Journal of Pharmacy & Pharmacology.  (London, UK)  V.2-21,
   1929-48.  For publisher information, see JPPMAB.  Volume(issue)/page/year:
   5,48,1932
 
TYPE OF TEST            : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - guinea pig
DOSE/DURATION           : 150 mg/kg
TOXIC EFFECTS :
   Behavioral - tremor
   Behavioral - convulsions or effect on seizure threshold
   Behavioral - ataxia
REFERENCE :
   QJPPAL Quarterly Journal of Pharmacy & Pharmacology.  (London, UK)  V.2-21,
   1929-48.  For publisher information, see JPPMAB.  Volume(issue)/page/year:
   5,48,1932
 
                            *** END OF RECORD ***