*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : UV1150800
CHEMICAL NAME           : 1H,3H-Pyrido(1,2-c)oxazine,
                          hexahydro-1-imino-4-phenyl-, hydrochloride, (E)-
CAS REGISTRY NUMBER     : 42510-63-4
LAST UPDATED            : 199404
DATA ITEMS CITED        : 2
MOLECULAR FORMULA       : C14-H18-N2-O.Cl-H
MOLECULAR WEIGHT        : 266.80
WISWESSER LINE NOTATION : T66 ANYOTJ BUM ER &GH
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * (E)-Hexahydro-1-imino-4-phenyl-1H,3H-pyrido(1,2-c)oxazine hydrochloride
   * trans-1-Imino-4-phenylhexahydro-1H,3H-pyrido(1,2-c)oxazine hydrochloride
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : >100 mg/kg
TOXIC EFFECTS :
   Brain and Coverings - recordings from specific areas of CNS
   Behavioral - excitement
   Vascular - BP elevation not characterized in autonomic section
REFERENCE :
   EJMCA5 European Journal of Medicinal Chemistry--Chimie Therapeutique.
   (Editions Scientifiques Elsevier, 29 rue Buffon, F-75005, Paris, France)
   V.9-    1974-  Volume(issue)/page/year: 15,111,1980
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 20 mg/kg
TOXIC EFFECTS :
   Brain and Coverings - recordings from specific areas of CNS
   Behavioral - excitement
   Vascular - BP elevation not characterized in autonomic section
REFERENCE :
   EJMCA5 European Journal of Medicinal Chemistry--Chimie Therapeutique.
   (Editions Scientifiques Elsevier, 29 rue Buffon, F-75005, Paris, France)
   V.9-    1974-  Volume(issue)/page/year: 15,111,1980
 
                            *** END OF RECORD ***