*** CHEMICAL IDENTIFICATION *** RTECS NUMBER : UV1155860 CHEMICAL NAME : Pyrido(2,3-d)pyrimidine-2,4-diamine, 6-((2,5-dimethoxyphenyl)methyl)-5-methyl- CAS REGISTRY NUMBER : 72732-56-0 BEILSTEIN REFERENCE NO. : 5768301 LAST UPDATED : 199612 DATA ITEMS CITED : 3 MOLECULAR FORMULA : C17-H19-N5-O2 MOLECULAR WEIGHT : 325.41 COMPOUND DESCRIPTOR : Drug Mutagen SYNONYMS/TRADE NAMES : * BW 301U * 2,4-Diamino-5-methyl-6-(2,5-dimethoxybenzyl)pyrido(2,3-d)pyrimidine * 6-((2,5-Dimethoxyphenyl)methyl)-5-methylpyrido(2,3-d)pyrimidine-2,4-diam ine * Piritrexim *** HEALTH HAZARD DATA *** ** ACUTE TOXICITY DATA ** TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - rat DOSE/DURATION : 1168 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : DRFUD4 Drugs of the Future. (J.R. Prous, S.A., Apartado de Correos 540, 08080 Barcelona, Spain) V.1- 1975/76- Volume(issue)/page/year: 11,140,1986 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intraperitoneal SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 500 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : EPXXDW European Patent Application. (U.S. Patent and Trademark Office, Foreign Patents, Washington, DC 20231) Volume(issue)/page/year: #0021292 ** MUTATION DATA ** TYPE OF TEST : DNA damage TEST SYSTEM : Rodent - mouse DOSE/DURATION : leu 10 REFERENCE : BJCAAI British Journal of Cancer. (Macmillan Press Ltd., Houndmills, Basingstoke, Hants. RG21 2XS, UK) V.1- 1947- Volume(issue)/page/year: 65,503,1992 *** END OF RECORD ***