*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : UV1173100
CHEMICAL NAME           : 10H-Pyrido(3,2-b)pyrimido(4,5-e)(1,4)thiazin-4-amine,
                          8-methyl-
CAS REGISTRY NUMBER     : 55740-63-1
LAST UPDATED            : 199712
DATA ITEMS CITED        : 1
MOLECULAR FORMULA       : C10-H9-N5-S
MOLECULAR WEIGHT        : 231.30
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * 8-Methyl-10H-pyrido(3,2-b)pyrimido(4,5-e)(1,4)thiazin-4-amine
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 30 mg/kg
TOXIC EFFECTS :
   Behavioral - changes in motor activity (specific assay)
   Lungs, Thorax, or Respiration - respiratory depression
   Nutritional and Gross Metabolic - body temperature decrease
REFERENCE :
   EJMCA5 European Journal of Medicinal Chemistry--Chimie Therapeutique.
   (Editions Scientifiques Elsevier, 29 rue Buffon, F-75005, Paris, France)
   V.9-    1974-  Volume(issue)/page/year: 12,249,1977
 
                            *** END OF RECORD ***