*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : UV0697000
CHEMICAL NAME           : 6H-Pyrido(2,3-b)(1,4)benzodiazepin-6-one,
                          5,11-dihydro-11-((2-((diethylamino)
                          methyl)-7-piperidinyl)acetyl)-
CAS REGISTRY NUMBER     : 102394-31-0
BEILSTEIN REFERENCE NO. : 4212983
LAST UPDATED            : 199612
DATA ITEMS CITED        : 4
MOLECULAR FORMULA       : C24-H31-N5-O2
MOLECULAR WEIGHT        : 421.60
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * AF-DX 116
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 1533 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   CDREEA Cardiovascular Drug Reviews.  (Raven Press, 1185 Avenue of the
   Americas, New York, NY  10036) V.6-    1988-  Volume(issue)/page/year:
   9,30,1991
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 83 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   CDREEA Cardiovascular Drug Reviews.  (Raven Press, 1185 Avenue of the
   Americas, New York, NY  10036) V.6-    1988-  Volume(issue)/page/year:
   9,30,1991
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 600 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   CDREEA Cardiovascular Drug Reviews.  (Raven Press, 1185 Avenue of the
   Americas, New York, NY  10036) V.6-    1988-  Volume(issue)/page/year:
   9,30,1991
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 50 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   CDREEA Cardiovascular Drug Reviews.  (Raven Press, 1185 Avenue of the
   Americas, New York, NY  10036) V.6-    1988-  Volume(issue)/page/year:
   9,30,1991
 
                            *** END OF RECORD ***