*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : UV6231785
CHEMICAL NAME           : 2-Pyrimidinamine,
                          4-(2-(bis(1-methylethyl)amino)ethoxy)-6-chloro-N-meth
                          yl-N-(4-methylphenyl)- 5-(methylthio)-,
                          monohydrobromide
CAS REGISTRY NUMBER     : 57259-28-6
LAST UPDATED            : 199703
DATA ITEMS CITED        : 2
MOLECULAR FORMULA       : C21-H31-Cl-N4-O-S.Br-H
MOLECULAR WEIGHT        : 503.99
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   *   N-Methyl-2-p-toluidin-4-(2'-N,N-diisopropylamino)-aethoxy-5-methylthio-6
     -chlorpyrimidin HBr
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : >900 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   GWXXBX German Offenlegungsschrift Patent Document.  (U.S. Patent and
   Trademark Office, Foreign Patents, Washington, DC 20231)
   Volume(issue)/page/year: #2503136
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 130 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   GWXXBX German Offenlegungsschrift Patent Document.  (U.S. Patent and
   Trademark Office, Foreign Patents, Washington, DC 20231)
   Volume(issue)/page/year: #2503136
 
                            *** END OF RECORD ***