*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : UV6260260
CHEMICAL NAME           : 2-Pyrimidinamine,
                          4-chloro-N,N-diethyl-6-((1-methyl-4-piperidinyl)oxy)-
                          5-(methylthio)-, monohydrobromide
CAS REGISTRY NUMBER     : 57259-19-5
LAST UPDATED            : 199703
DATA ITEMS CITED        : 2
MOLECULAR FORMULA       : C15-H25-Cl-N4-O-S.Br-H
MOLECULAR WEIGHT        : 425.87
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   *   2-Diaethylamino-4-((4')-N-methylpiperidyl)-oxy-5-methylthio-6-chloropyri
     midin hydrobromid
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 525 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   GWXXBX German Offenlegungsschrift Patent Document.  (U.S. Patent and
   Trademark Office, Foreign Patents, Washington, DC 20231)
   Volume(issue)/page/year: #2503136
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 59 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   GWXXBX German Offenlegungsschrift Patent Document.  (U.S. Patent and
   Trademark Office, Foreign Patents, Washington, DC 20231)
   Volume(issue)/page/year: #2503136
 
                            *** END OF RECORD ***