*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : UV8139525
CHEMICAL NAME           : 2,4-Pyrimidinediamine, 6-chloro-N(sup
                          4)-(2-(diethylamino)ethyl)-N(sup 2)-methyl-5-
                          (methylthio)-N(sup 2)-phenyl-, dihydrobromide
CAS REGISTRY NUMBER     : 55416-92-7
LAST UPDATED            : 199703
DATA ITEMS CITED        : 2
MOLECULAR FORMULA       : C18-H26-Cl-N5-S.2Br-H
MOLECULAR WEIGHT        : 541.84
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   *   2-N-Methyl-N-phenylamino-4-(2'-diethylamino)ethylamino-5-methylthio-6-ch
     loropyrimidine 2HBr
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 225 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   USXXAM United States Patent Document.  (U.S. Patent Office, Box 9,
   Washington, DC 20231)  Volume(issue)/page/year: #3968214
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 43 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   USXXAM United States Patent Document.  (U.S. Patent Office, Box 9,
   Washington, DC 20231)  Volume(issue)/page/year: #3968214
 
                            *** END OF RECORD ***