*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : UV8141800
CHEMICAL NAME           : 2,4-Pyrimidinediamine,
                          5-((3,5-dimethoxy-4-(methylthio)phenyl)methyl)-
CAS REGISTRY NUMBER     : 68902-57-8
LAST UPDATED            : 199712
DATA ITEMS CITED        : 1
MOLECULAR FORMULA       : C14-H18-N4-O2-S
MOLECULAR WEIGHT        : 306.42
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * 2,4-Diamino-5-(3',5'-dimethoxy-4'-methylthio)benzylpyrimidine
   * 5-((3,5-Dimethoxy-4-(methylthio)phenyl)methyl)-2,4-pyrimidinediamine
   * Methioprim
   * Methioprim (bacteriostat)
   * Metioprim
   * Ro 12-6995
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : >5 gm/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   USXXAM United States Patent Document.  (U.S. Patent Office, Box 9,
   Washington, DC 20231)  Volume(issue)/page/year: #4180578
 
                            *** END OF RECORD ***